The WashU Medicine ALS Center provides quality care, state-of-the-art treatment, precision medicine, and research opportunities to patients diagnosed with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.
press release
New ALS drug stabilizes decline with improved strength, mobility for some (Links to an external site)
Long-term use of tofersen slows ALS disease progression in people with a genetic subtype, provides hope for treating other forms of ALS. Read more »

ALS patient care
Our St. Louis ALS team, consisting of physicians, clinicians, researchers and experts, collaborates to evaluate patient needs, create individualized clinical care plans, and implement recommended clinical services.

Clinical trials
Clinical trials transform promising laboratory research into life-enhancing treatments. Patients at our center have access to leading-edge clinical trials which focus on personalized medicine to improve the understanding, treatment, and prevention of ALS.
Programs & Labs
Miller Laboratory
Translational Research
Dedicated to understanding neurodegenerative diseases including ALS and dementias in order to develop new, effective and safe treatments. We focus on translational neuroscience, new therapeutic approaches for neurodegenerative diseases, and precision medicine.
Ly Laboratory
Neurology
Cindy Ly’s laboratory specializes in researching muscular dystrophy, myositis, myasthenia gravis, neuromuscular diseases, ALS and peripheral neuropathy.
Tofersen Clinic
Clinical Program for SOD-1
Sean E. Smith, MD, spearheads our Tofersen Clinic, dedicated to providing treatment for patients with Amyotrophic Lateral Sclerosis (ALS) caused by a mutation in the SOD1 gene.
At-Risk ALS Program
Preventative Care
The At-Risk ALS clinical program is for individuals who have been identified as having an elevated risk for developing Amyotrophic Lateral Sclerosis (ALS) but who are currently healthy and without symptoms (presymptomatic).
News & Recognition
Get involved

Join our email list
Sign up for our email list
to receive updates from the WashU ALS Center.

Clinical trials
Participate in a trial or study that relate to the cause and treatment of ALS.

Donate
Donate online.
Donate by mail.
Donate human tissue.
