The WashU Medicine ALS Center provides quality care, state-of-the-art treatment, precision medicine, and research opportunities to patients diagnosed with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.


press release
Another Tomorrow follows patients, families, physicians and researchers standing at the edge of a medical turning point.

Amber with ALS Patient

ALS patient care

Our St. Louis ALS team, consisting of physicians, clinicians, researchers and experts, collaborates to evaluate patient needs, create individualized clinical care plans, and implement recommended clinical services.

Bucelli with ALS Patient

Clinical trials

Clinical trials transform promising laboratory research into life-enhancing treatments. Patients at our center have access to leading-edge clinical trials which focus on personalized medicine to improve the understanding, treatment, and prevention of ALS.

Programs & Labs

Miller Laboratory

Translational Research

Dedicated to understanding neurodegenerative diseases including ALS and dementias in order to develop new, effective and safe treatments. We focus on translational neuroscience, new therapeutic approaches for neurodegenerative diseases, and precision medicine.

Ly Laboratory

Neurology

Cindy Ly’s laboratory specializes in researching muscular dystrophy, myositis, myasthenia gravis, neuromuscular diseases, ALS and peripheral neuropathy.

Tofersen Clinic

Clinical Program for SOD-1

Sean E. Smith, MD, spearheads our Tofersen Clinic, dedicated to providing treatment for patients with Amyotrophic Lateral Sclerosis (ALS) caused by a mutation in the SOD1 gene.

At-Risk ALS Program

Preventative Care

The At-Risk ALS clinical program is for individuals who have been identified as having an elevated risk for developing Amyotrophic Lateral Sclerosis (ALS) but who are currently healthy and without symptoms (presymptomatic).

News & Recognition

International trials of tofersen
A new drug has been approved by the Food and Drug Administration (FDA) for a rare, inherited form of ALS caused by mutations in the gene SOD1.

Meet Roger; clinical trial participant
When Roger was diagnosed with ALS, he decided to participate in a clinical trial at the ALS Center at WashU Medicine.

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Clinical trials

Participate in a trial or study that relate to the cause and treatment of ALS.

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